Support When Every Step Hurts

Red Light Therapy for Sprains and Ligament Injuries in Pets

Anderson

Written by: Alon Landa
Medically reviewed by: Kristy Williams, CVT, CCFT (Specialties: Pet rehabilitation, pain management, photobiomodulation)

Reviewed: July 2026
Updated: July 2026

A sprain can change everything.

One bad landing. One sharp turn. One wild sprint across the yard. Suddenly, your dog is limping, holding up a leg, struggling on stairs, or refusing to play.

Ligament injuries can be painful and slow to heal. They can also be frustrating because rest takes time, surgery is not always the first choice, and pain medication can only do so much.

Red light therapy gives pet owners another way to support the healing process.

Luma brings red light therapy and near-infrared light therapy home, helping support pain relief, reduce inflammation, improve blood flow, and assist soft tissue repair during recovery from sprains, ligament injuries, CCL tears, ACL injuries, orthopedic surgery, and mobility setbacks.

Is Red Light Therapy right for your dog?

Gideon

Is red light therapy effective for sprains and ligament injuries in dogs?`

Red light therapy can help support recovery from sprains and ligament injuries by reducing inflammation, improving pain relief, supporting collagen production, and helping repair injured soft tissue. It may be useful during conservative management, after surgery, or as part of a vet-guided physical therapy plan.

Red light therapy cannot repair a fully torn ligament on its own, and it should not delay veterinary care when a pet has severe pain, swelling, instability, or sudden lameness.

What are sprains and ligament injuries in pets?

A sprain happens when a ligament is stretched, strained, partially torn, or fully torn.

Ligaments are strong bands of tissue that connect bones and help stabilize joints. When a ligament is injured, the joint can become painful, swollen, unstable, and difficult to use.

In dogs, one of the most common ligament injuries is a cranial cruciate ligament injury, often called a CCL tear. Many pet owners know it as an ACL tear because it is similar to the ACL injury people get in the knee.

Cats can get sprains and soft tissue injuries too. A hard jump, rough play, a fall, or a twist can injure a ligament, tendon, or surrounding muscle.

Common signs of a sprain or ligament injury

You may notice:

  • Limping or favoring one leg
  • Stiffness after rest
  • Swelling around a joint
  • Trouble standing up
  • Reluctance to run, jump, or climb stairs
  • Yelping when touched
  • Holding one leg up
  • Sitting with one leg kicked out
  • Reduced activity
  • A sudden change in mood or movement
  • Muscle loss over time from using the leg less

Some pets show clear pain right away. Others compensate quietly.

That is why early care matters.

When to call your vet

Contact your vet if your pet has:

  • Sudden lameness
  • Severe pain
  • Refusal to put weight on a leg
  • Visible swelling
  • Joint instability
  • A known fall or twist
  • Limping that lasts more than 24 to 48 hours
  • A suspected CCL tear
  • Pain that keeps returning
  • Worsening mobility

A sprain can look like a fracture, dislocation, tendon injury, torn ligament, arthritis flare, hip issue, spinal issue, or nerve problem. A vet can help confirm what is actually going on and guide the right treatment.

Friendly tan dog with a wide open mouth and blue-eyed gaze, standing on grass outdoors.

“Anderson was seen by 2 orthopedic doctors who recommended ACL repair on one or both legs. We opted for a conservative approach of rest, acupuncture, and laser therapy. After a recommendation from our vet, Dr. Karen Collins, we purchased our Luma. Anderson is in year 2 of pain-free happiness. He loves his laser therapy! Thank you, Luma.”

With gratitude, Michelle Scharff Anderson

How Luma helps with sprains and ligament injuries

Luma is a handheld red light therapy device designed for at-home pet care.

It uses two therapeutic wavelengths:

WavelengthWhat it supportsWhy it matters for sprains and ligament injuries
635nm red lightSurface tissue response, circulation, and inflammation support from visible red lightHelpful for soreness, swelling, and soft tissue irritation near the skin, including support for the pet’s skin and tissue close to the surface
850nm near-infrared lightDeeper tissue supportHelps light reach deeper structures around joints, ligaments, tendons, and muscles

Photobiomodulation, also called red light therapy, low-level laser therapy, LED therapy, cold laser, near-infrared therapy, and PBM therapy, refers to the same therapeutic category using light energy to influence cellular activity.

In plain terms, Luma helps stimulate cellular activity to support healing and improve cellular energy production while the body does the repair work it is already trying to do.

1. Supports cellular energy

When tissue is injured, cells need more energy to repair.

Red light therapy helps support ATP production, giving cells an energy boost for repair, recovery, and normal function. Better cellular energy can help injured tissue move through the healing process more efficiently.

2. Helps reduce inflammation

Inflammation is part of healing, but too much inflammation can increase pain, swelling, stiffness, and joint discomfort.

Red light therapy can help reduce inflammatory signaling in soft tissue injuries, which may help ease pain and support healing. For sprains and ligament injuries, that may support easier movement and better comfort during recovery.

3. Helps with pain relief

Pain changes how pets move.

A dog with a sore knee may shift weight to the other leg. A cat with a sprained leg may hide, stop jumping, or move less. Over time, compensation can strain other joints and muscles.

Red light therapy can help improve pain relief by calming irritated tissue, supporting endorphin response, and reducing sensitivity in the treatment area.

4. Supports collagen production

Ligaments and tendons rely on collagen.

During repair, the body uses fibroblasts to help build new collagen fibers. Red and near-infrared light therapy may support fibroblast activity and collagen formation, which matters for ligament injuries, tendon irritation, and joint support.

5. Improves local blood flow

Healing tissue needs oxygen and nutrients.

Red light therapy can support blood circulation around the treatment area, helping deliver oxygen and nutrients while supporting waste removal from injured tissue.

6. Helps pets tolerate recovery

Sprains and ligament injuries often require restricted activity, slow return to movement, physical therapy, weight control, braces, medication, surgery, and other treatments.

Luma gives pet owners a powerful tool they can use at home for promoting recovery while their pet follows a vet-guided plan.

That matters when every clinic trip is stressful. It matters when a 105-pound dog with a torn ligament needs repeated therapy. It matters when healing takes weeks or months, especially when home care supports the pet’s well being.

Want to know if Luma could relieve your pet’s pain

Ella

MedcoVet Dog - Roxy

“Roxy had developed knee and leg issues and had been limping for several months prior to reaching out to Medcovet to try the Luma. We had tried medication and nothing seemed to help her. With 2x daily use with the Luma, Roxy was able to finally put weight on her leg without limping and walk/play.” -Renee Carter

Sprains happen when ligaments—the sturdy bands connecting bones—are stretched or torn. Dogs are especially prone to ligament injuries like CCL (cranial cruciate ligament) tears, which can make even standing a struggle. Cats can suffer soft tissue injuries too, especially after high jumps or rough play.

Why Luma is a strong fit for ligament injury recovery

Ligament recovery usually needs consistency and a comprehensive care plan, not a single intervention.

One treatment rarely changes the whole case. Pets often need repeated support over time, especially during the early healing phase or after surgery.

Luma makes repeat therapy easier because it can be used at home.

Luma is helpful for sprains and ligament injuries because it is:

  • At-home: No repeated clinic trips for every session
  • Non-invasive: No needles, sedation, or stressful setup
  • Drug-free: Helpful support alongside your vet’s plan
  • Quick to use: Sessions can fit into a normal daily routine
  • Designed for pets: The comb-style head helps part fur so light reaches the skin
  • Useful for repeat care: Soft tissue healing often needs consistent support
  • Clinician-guided: MedcoVet can help pet owners understand where and how to use Luma

Luma does not diagnose a ligament injury. It does not replace surgery when surgery is needed. It does not replace rest, braces, physical therapy, anti-inflammatory drugs, pain medication, or veterinary care.

It gives your pet’s body extra support during recovery.

That is the point.

Can red light therapy help a CCL or ACL injury?

Red light therapy may help reduce pain, inflammation, swelling, and soft tissue stress around a CCL injury, often called an ACL injury by pet owners.

For partial tears, red light therapy may be used as part of conservative management with rest, weight control, bracing, pain control, and physical therapy. It may also be used when chronic conditions such as arthritis affect the same limb or complicate recovery. For full tears or unstable knees, surgery may still be the best option.

Luma can be useful after CCL surgery too. It may promote healing and support faster recovery for pain, inflammation, incision healing, muscle tightness, and gradual return to movement.

Ask your vet which category your pet is in.

A partial sprain, a full tear, and a post-surgery knee need different plans, and overall health influences which recovery plan is appropriate.

How Luma Helps with Sprains & Ligament Injuries

MedcoVet Dog - Lucy
“I got Lucy in my mid-twenties, and it’s been me and here side-by-side for almost 10 years now. She has always loved to be active and fun around. She tore her ACL a few months ago, and unfortunately, due to her age and overall hip condition, the doctor said she was not a good candidate for surgery. They recommended red light therapy as an alternative. After a few weeks of loading her in the car (not an easy task for a 105-pound dog with a torn leg), taking her to the vet (where she gets pretty stressed,) and sometimes having to wait for a while for treatment, I was beginning to lose hope that she would have successful healing. I was introduced to Medcovet, where Chris was unbelievably thoughtful and helpful. She took time to truly understand Lucy’s condition and make recommendations specific to her. In addition to the personalized attention and care, the cost of this therapy was substantially lower than what I was paying at the vet! Felt like a win, win, win. After several months, Lucy is back to normal, and we are thrilled! SO thankful to have found Medcovet!” -Alison Earl

What the research says about red light therapy for sprains and ligament injuries

Red light therapy and low-level laser therapy have been studied for soft tissue injuries, tendon healing, ligament healing, pain, inflammation, blood flow, wound healing, orthopedic recovery, and tendon and ligament injuries.

The findings are useful for pet owners because sprains and ligament injuries depend on the same basic repair systems:

  • Inflammation control
  • Cellular energy production
  • Collagen formation
  • Blood flow
  • Tissue remodeling
  • Pain control
  • Gradual return to load and movement

Research in animals and clinical settings suggests that red and near-infrared light therapy may support soft tissue repair, reduce pain, reduce swelling, improve function, and speed healing when used with the right wavelength, dose, timing, and treatment plan; some reports on photobiomodulation also note recovery up to 50% faster than conventional methods alone.

Luma uses 635nm red light and 850nm near-infrared light. These wavelengths were chosen to support both surface-level tissue response and deeper tissue response around joints, ligaments, tendons, and muscles.

The details matter.

A red light therapy device should use specific wavelengths and deliver enough irradiance to support a therapeutic effect. Placement also matters, especially for pets with thick fur or deeper injuries. With the right wavelength, dose, and timing, PBM therapy may be used across acute and chronic conditions. Luma’s comb-style design helps part the fur so the light can get closer to the skin.

Want to understand the larger science behind photobiomodulation? Read The Science of Red Light Therapy.

Want a pet-parent guide to red light therapy for mobility, pain, and healing? Read Red Light Therapy for Dogs.

How to use Luma for a sprain or ligament injury at home

Every injury is different. A mild wrist sprain, a partial CCL tear, and post-op knee recovery need different plans.

Start with your vet’s diagnosis. Then build around it.

A practical at-home care plan may include:

1. Restrict activity

Limit running, jumping, stairs, and rough play with other dogs. Use leash walks for bathroom breaks if your vet recommends it.

This can feel boring. It is also one of the most important parts of soft tissue healing.

2. Use the right surface

Slippery floors can make ligament injuries worse.

Use rugs, runners, yoga mats, or traction socks to help your pet move safely through the house. Block stairs if needed.

3. Support healthy weight

Extra weight adds stress to injured joints and ligaments.

Even small weight changes can reduce pressure on the knees, hips, shoulders, and back.

4. Apply Luma over the treatment area

Use Luma directly over the injured joint or soft tissue area based on your protocol. Sessions typically last 5 to 20 minutes, depending on the area treated and your plan. Part the fur so the light reaches the skin, use recommended eye protection for handlers, and follow device guidance around the eyes during treatment so red light exposure stays focused on the target area.

For knee injuries, your clinician may guide you to treat around the knee, surrounding muscles, and compensation areas such as the hips or opposite leg.

5. Track small changes

Track these changes over time to gauge improved mobility and your pet’s overall response to treatment:

  • More even weight-bearing
  • Less limping
  • Less stiffness after rest
  • Easier standing
  • Better comfort on leash walks
  • Less swelling
  • Better mood
  • More confidence using the injured leg

6. Return to activity slowly

A pet may feel better before the ligament is fully healed.

That is where many setbacks happen. Build activity gradually and follow your vet’s timeline.

Get a personalized Luma protocol for your pet

Ghillie

What improvement can look like

Improvement may be subtle at first, reflecting not only mobility gains but also comfort, well being, and the pet’s health during recovery.

A dog may place the paw down more often. A cat may jump onto a lower chair again. A senior dog may stand up with less hesitation. A post-surgery pet may rest more comfortably.

Those changes matter.

Common signs of progress include:

  • Less limping
  • More comfortable standing
  • Better tolerance for short walks
  • Less guarding
  • Less licking at the sore joint
  • Reduced swelling
  • Easier transitions from lying down to standing
  • Better sleep
  • Brighter mood

Call your vet if pain worsens, swelling increases, your pet stops using the leg, or mobility declines.

Safe, soothing, and designed for at-home use

MedcoVet Dog - Bran
“The luma helped speed Bran’s recovery and daily treatments made him have a far more complete recovery.” -Julie

Luma was built for normal homes, real pets, and repeat care.

Most pets find sessions relaxing, and some may even doze off during treatment. Sessions are quiet. There is no sedation. There are no needles. There is no stressful clinic room.

Pets with sprains and ligament injuries often need multiple sessions over time. Luma makes that easier.

Luma can be used for:

  • Sprains
  • CCL injuries
  • ACL injuries
  • Soft tissue injuries
  • Some skin conditions, and in select cases support around open wounds
  • Tendon irritation
  • Recovery support after surgical procedures
  • Joint discomfort
  • Arthritis-related compensation and chronic pain
  • Senior dog stiffness
  • Mobility support

Use Luma with clinician guidance, especially after surgery or when a ligament tear is suspected.

Talk with a clinician about your pet’s injury

Hazel Moon

Testimonials: Real pets. Real relief.

Sprains and ligament injuries can make pets feel older overnight.

They move less. They hesitate. They stop doing the little things that make them feel like themselves.

These stories show how pet owners used Luma as part of their pet’s recovery plan, from conservative care to post-surgery support. Some pets needed help with pain. Some needed support after orthopedic surgery. Some needed a way to receive regular light therapy at home without stressful clinic trips.

Categories
1-8 of 21 results
  • Maverick

    “The Luma helped Maverick’s recovery process and brought him back to better health, movement and agility than before using the…”

  • Jacques

    “Our pup Jacques tore his CCL at 11 year old and the Luma help so much with his post surgery…”

  • Olive

    “Olive was only a year old when she was diagnosed with grade 3 bilateral luxating patellas. We found an amazing…”

  • Morris Samuel Berry

    “At a mere 6 months of age and exuberant Morris tried to steal a toy from his brother. In the…”

  • Noel

    “The Luma helped Noel recover through multiple operations as an 8-week-old puppy. Noel’s leg was severely broken when her original…”

  • Penni

    “The Luma was so helpful during Penni’s recovery from surgery. It was effective for both pain control and wound healing.…”

  • Ruger

    “Ruger has always been a dog who finds joy in running, hiking, and wrestling with other dogs. After tearing his…”

  • Daisy

    “Daisy is a large (pyranesse mix) dog that thinks she is a pro athlete. She partially tore her cruciate ligament…”

Want to know whether Luma could help your pet?

Mizzy

Clinical questions about red light therapy for sprains and ligament injuries

Red light therapy can support the healing environment around injured tissue, but it cannot reconnect a fully torn ligament on its own. It may help reduce pain, reduce inflammation, support collagen activity, and assist recovery as part of conservative care or post-surgery rehabilitation.

Luma may help support comfort and recovery for dogs with CCL injuries, which many pet owners call ACL injuries. It may be used with clinician guidance during conservative management, after surgery, or alongside physical therapy. A full tear or unstable knee should be assessed by a vet.

Red light therapy may be used before surgery to support pain and inflammation control, and after surgery to support comfort, swelling reduction, incision healing, and mobility recovery. Your clinician should guide timing around the surgery date and incision site.

Frequency depends on the injury, pain level, treatment area, coat type, and recovery plan. Some pets may use Luma more often during the acute phase, then taper as comfort and mobility improve. A MedcoVet clinician can help guide the starting plan.

Mild sprains may improve over days to weeks. More serious ligament injuries can take several weeks to months, especially if the joint is unstable or surgery is needed. Healing depends on rest, diagnosis, weight, activity control, pain management, and the severity of the injury.

Some pets may need less reliance on pain medication over time when red light therapy is part of a successful care plan, but medication changes should always be made with your vet. Do not stop anti-inflammatory drugs or pain medication without veterinary guidance.

Red light therapy is commonly used for senior dogs with arthritis, stiffness, and other chronic conditions that affect comfort and movement. Senior pets often have multiple issues at once, so a clinician-guided plan is best.

Yes. Thick fur can block some light from reaching the skin. Luma’s comb-style head helps part the fur so red light and near-infrared light can reach the treatment area more effectively.

Yes, cats can use Luma with the right handling and protocol. Cats can develop sprains, soft tissue injuries, and post-jump soreness. If your cat is hiding, limping, or avoiding normal movement, check with your vet.

Avoid relying on at-home treatment alone if your pet has severe pain, sudden lameness, visible swelling, obvious joint instability, a suspected fracture, fever, neurological signs, or a wound that needs medical care. Call your vet.

Clinical summary

Mechanism

Photobiomodulation, also called red light therapy, low-level laser therapy, LED therapy, cold laser, and near-infrared therapy, uses specific wavelengths of visible red and near-infrared light to stimulate cellular activity and improve cellular energy production. In sprains and ligament injuries, therapeutic light is applied over the injured joint or soft tissue area to support these effects. Proposed mechanisms include increased ATP production, reduced inflammatory signaling, improved microcirculation, pain modulation, fibroblast activity, collagen production, and support for cellular repair.

Evidence level

Evidence for red light therapy in sprains, ligament injuries, and soft tissue recovery is moderate and still developing. Animal and clinical studies suggest potential benefit for inflammation, pain, collagen synthesis, tendon and ligament repair, wound healing, and post-operative recovery, though veterinarians recommend using it as part of a broader treatment plan rather than as a standalone cure. Results depend on diagnosis, injury severity, treatment timing, wavelength, irradiance, dose, treatment frequency, and whether the joint remains mechanically stable.

When it works best

Red light therapy may work best for mild to moderate sprains, partial ligament injuries, post-surgery recovery, arthritis-related compensation, soft tissue inflammation, muscle strains, chronic conditions, and recovery plans that include activity restriction, weight control, pain management, and physical therapy. It is especially useful when repeated therapy sessions are needed over time.

When not to use

Red light therapy should not delay veterinary care when a pet has severe pain, refusal to bear weight, major swelling, suspected fracture, unstable joint, complete ligament rupture, neurological signs, fever, or worsening mobility. It should also be used with veterinary guidance in pets with cancer, pregnancy, complex illness, surgical incisions, or unexplained pain, since treatment choices depend on the pet’s overall health and veterinary evaluation.

Summary: Why use Luma for sprains and ligament injuries?

What Luma supportsWhy it matters
Pain reliefHelps pets rest and move more comfortably
Reduced inflammationHelps calm swelling and tissue irritation
ATP productionGives cells more energy for repair
Blood flowSupports oxygen and nutrient delivery
Collagen activitySupports ligament and tendon repair processes
Post-surgery comfortHelps support recovery after orthopedic procedures
At-home repeat careMakes consistent therapy easier for pet owners

Try Luma for your pet’s sprain or ligament injury

A ligament injury can make every step feel hard.

You do have options.

If your dog or cat is recovering from a sprain, CCL injury, ACL injury, soft tissue injury, orthopedic surgery, or chronic joint discomfort, Luma may be a helpful part of their recovery plan.

We can help you understand what red light therapy may support, when to call your vet, and how to use Luma safely at home.

Take the 2-minute quiz: Is red light therapy right for your dog?

Sprite

Evidence Citations

  • 830 nm light-emitting diode (led) phototherapy significantly reduced return-to-play in injured university athletes: a pilot study.

    By Foley

    • 2016

    • Journal: Laser Ther

    Abstract: “Over a 15-month period, a total of 395 injuries including sprains, strains, ligament damage, tendonitis and contusions were treated” “The average LED-mediated RTP in the 65 subjects was significantly shorter at 9.6 days, compared with the mean anticipated RTP of 19.23 days (p = 0.0066, paired two-tailed Student’s t-test). “A subjective satisfaction survey was carried out among the 112 students with injuries incurred from January to May, 2015. Eighty-eight (78.5%) were either very satisfied or satisfied, and only 8 (7.2%) were dissatisfied.”

    One Sentence Outcome:LED phototherapy was associated with a shorter return-to-play time in injured university athletes, including sprains, strains, ligament damage, tendonitis and contusions.

    Study Parameters:Human Single-arm (retrospective?) 65 participants ⌛ ~1-2 weeks per patient; Sessions: 3-6 on average; Treatment time: 1200 sec

    Device Parameters: Wavelength: 830 nm; Irradiance: 0.05 W/cm²; Dose: 60 J/cm²

    Evidence Level:Pilot study|Retrospective clinical study

    Study Type: Human Single-arm (retrospective?) 65 participants ⌛ ~1-2 weeks per patient

    Outcome Direction: Positive

  • Effects of High Intensity Laser Therapy in the Treatment of Tendon and Ligament Injuries in Performance Horses

    By Zielińska

    • 2020

    • Journal: Animals (Basel)

    Abstract: “After the treatment, pain, swelling and lameness were significantly improved by HILT compared with the control group (p = 0.023, 0.008 and 0.044, respectively). No significant changes were found in lesion echogenicity degree between both groups in measurements taken during treatment (p = 0.188) and after treatment (p = 0.070). For lesion percentage reduction, the statistical modelling showed a significant improvement in the HILT group compared with the control group during (p = 0.038) and after treatment (p = 0.019). In conclusion, HILT promoted analgesic and anti-oedema effects, with visual lameness reduction in horses with tendon and ligament injuries, and reduced lesion percentage but did not influence change in lesion echogenicity.”

    One Sentence Outcome:High-intensity laser therapy was associated with improved pain, swelling, lameness and lesion reduction in performance horses with tendon and ligament injuries.

    Study Parameters:Horse

    Device Parameters: Wavelength: 808+ 980 nm

    Evidence Level:Veterinary clinical study

    Study Type: Horse

    Outcome Direction: Mixed / null

  • Short- and long term follow-up of 150 sports horses diagnosed with tendinopathy or desmopathy by ultrasonographic examination and treated with high-power laser therapy

    By Pluim

    • 2018

    • Journal: Res Vet Sci

    Abstract: “Notwithstanding the wide variability in lameness score at admission, there was a statistically significant overall improvement in both lameness and ultrasonographic scores the day after cessation of laser therapy (week 2) and 4 weeks later (week 6), across all types and stages of tendinopathy or desmopathy and both for horses diagnosed with a single disorder and for horses suffering from multiple causes of lameness. The lack of a control group precludes drawing of any conclusions about causal effects, but this finding can be considered quite interesting, as the improvement manifests after a much shorter time interval than described in literature for other treatment modalities.” Comment: Dose parameters not reported.

    One Sentence Outcome:In 150 sports horses with tendinopathy or desmopathy treated with high-power laser therapy, lameness and ultrasonographic scores improved over short-term follow-up, although causality is limited by lack of a control group.

    Study Parameters:Horse

    Device Parameters: Wavelength: 635+ 660+ 810+ 980 nm

    Evidence Level:Veterinary clinical study

    Study Type: Horse

    Outcome Direction: Positive

  • The use of Bioptron light (polarized, polychromatic, non-coherent) therapy for the treatment of acute ankle sprains

    By Stasinopoulos et al.

    • 2017

    • Journal: Disabil Rehabil

    Abstract: “The test group showed the largest magnitude of improvement for all evaluations at treatment five, and the between-group differences observed were statistically significant (p < 0.0005 for each)." "These data provide preliminary evidence of the efficacy of Bioptron light therapy supplemented with cryotherapy for the treatment of acute ankle sprains; however, larger studies are required to confirm these results."

    One Sentence Outcome:The test group showed the largest magnitude of improvement for all evaluations at treatment five, and the between-group differences observed were statistically significant (p < 0.0005 for each)." "These data provide preliminary evidence of the efficacy of...

    Study Parameters:Human; Randomized trial, sham-controlled; 50 participants; ⌛ 5 days; Cryotherapy vs cryotherapy+PBM; ; Polychromatic light

    Device Parameters: wavelength 480- 3400 nm; irradiance 0.040 W/cm2; sessions 5 / 5 days

    Evidence Level:Clinical RCT

    Study Type: Randomized controlled trial

    Outcome Direction: positive

  • Low-level laser treatment can reduce edema in second degree ankle sprains.

    By Stergioulas A et al.

    • 2004

    • Journal: J Clin Laser Med Surg

    Abstract: “A three by three repeated measures ANOVA with a follow up post hoc test revealed that the group treated with the RICE and an 820-nm GaA1As diode laser presented a statistically significant reduction in the volume of the edema after 24 h (40.3 +/- 2.4 mL, p < 0.01), 48 h (56.4 +/- 3.1 mL, p < 0.002), and 72 h (65.1 +/- 4.4 mL, p < 0.001)."

    One Sentence Outcome:A three by three repeated measures ANOVA with a follow up post hoc test revealed that the group treated with the RICE and an 820-nm GaA1As diode laser presented a statistically significant reduction in the volume of the edema after 24 h (40.3 +/- 2.4 mL, p…

    Study Parameters:Human; Randomized trial, double-blind; 47 participants; ⌛ 3 days

    Device Parameters: wavelength 820.0 nm; power 40.0 mW; fluence 10 J/cm2; sessions 6 / 3 days

    Evidence Level:Clinical RCT

    Study Type: Randomized controlled trial

    Outcome Direction: positive

  • Effect of low-level laser therapy on healing of medial collateral ligament injuries in rats: an ultrastructural study.

    By Delbari et al.

    • 2007

    • Journal: Photomed Laser Surg

    Abstract: “On day 12, the fibril dimension of group 2 and their density were higher than of groups 1 and 3.” “Although we could not find significant difference between density of fibrils of laser groups and other groups, the p value shows a difference almost at the range of significance (p _x0004_= 0.059).”

    One Sentence Outcome:On day 12, the fibril dimension of group 2 and their density were higher than of groups 1 and 3.” “Although we could not find significant difference between density of fibrils of laser groups and other groups, the p value shows a difference almost at the…

    Study Parameters:Rat; Dose response

    Device Parameters: wavelength 633.0 nm; fluence 0.01 1.20 J/cm2; duration 1 120 sec; sessions 21.0

    Evidence Level:Preclinical animal study

    Study Type: Animal model

    Outcome Direction: positive

  • Therapeutic low energy laser improves the mechanical strength of repairing medial collateral ligament.

    By Fung et al.

    • 2002

    • Journal: Lasers Surg Med

    Abstract: “The UTS of laser and sham groups were comparable.”

    One Sentence Outcome:The UTS of laser and sham groups were comparable.

    Study Parameters:Rat

    Device Parameters: wavelength 660.0 nm; fluence 31.6 63.2 J/cm2; duration 450 900 sec; sessions 1.0

    Evidence Level:Preclinical animal study

    Study Type: Animal model

    Outcome Direction: mixed

  • Fractionated irradiation in photobiomodulation therapy of ankle sprain.

    By Calin et al.

    • 2019

    • Journal: Am J Phys Med Rehabil

    Abstract: “Reflectance data analysis showed significant changes in group 1 (p = 0.027). There was also an ankle function score improvement more in group 1 than in group 2, with a significant short-term effect (p = 0.011) but without significant long-term effects (p = 0.178). Compared with group 2, group 1 had an immediate effect on pain reduction, but no long-term effect (p = 0.074).” “Combined with standard treatment, fractionated irradiation photobiomodulation therapy has been shown to have favorable short-term effects on the recovery of patients with ankle sprains, but its long-term effects should be improved.” Note: This single study seems to have two PubMed entries for some reason, possibly because of a mistake! (The other one: https://www.ncbi.nlm.nih.gov/pubmed/31318750 )

    One Sentence Outcome:Reflectance data analysis showed significant changes in group 1 (p = 0.027). There was also an ankle function score improvement more in group 1 than in group 2, with a significant short-term effect (p = 0.011) but without significant long-term effects (p =…

    Study Parameters:Human; Randomized trial; 19 participants; ⌛ 6 sessions on 3 consecutive days -> 6-week follow-up

    Device Parameters: wavelength 635.0 nm; power 15.0 mW; fluence 4.5 + 9.0 J/cm2; sessions 6 / 3 days

    Evidence Level:Clinical RCT

    Study Type: Randomized controlled trial

    Outcome Direction: positive

  • Evaluation of the therapeutic effects of led (λ627 ± 10 nm) on the initial phase of ankle sprain treatment: a randomised placebo-controlled clinical trial.

    By de Moraes Prianti et al.

    • 2018

    • Journal: Lasers Med Sci

    Abstract: “The group treated with LED showed statistically decreased pain compared to the placebo group in both the VAS (85.79 vs 55.73%) and McGill questionnaire (83.33 vs 52.52%). The reduction of oedema in the LED group on the 3rd and 6th days after therapy was statistically superior to that in the placebo (p < 0.0001). Based on the results of this study, treatment with LED, using the tested dose, is effective for pain and oedema in the initial phase of ankle sprains."

    One Sentence Outcome:The group treated with LED showed statistically decreased pain compared to the placebo group in both the VAS (85.79 vs 55.73%) and McGill questionnaire (83.33 vs 52.52%). The reduction of oedema in the LED group on the 3rd and 6th days after therapy was…

    Study Parameters:Human; Randomized trial, sham-controlled; 40 participants; ⌛ 6 days; LED phototherapy

    Device Parameters: wavelength 627.0 nm; power 60.0 mW; energy 100 (10p) J; duration 1670 (10p) sec; sessions 6 / 6 days

    Evidence Level:Clinical RCT

    Study Type: Randomized controlled trial

    Outcome Direction: positive

  • Low-level laser therapy prevents degenerative morphological changes in an experimental model of anterior cruciate ligament transection in rats

    By Bublitz et al.

    • 2014

    • Journal: Lasers Med Sci

    Abstract: “Initial signs of tissue degradation were observed in CG. Interestingly, laser-treated animals presented a better tissue organization, especially at the fluence of 10 J/cm(2). Furthermore, laser phototherapy was able of modulating some of the aspects related to the degenerative process, such as the prevention of proteoglycans loss and the increase in cartilage area. However, LLLT was not able of modulating chondrocytes proliferation and the immunoexpression of markers related to inflammatory process (IL-1 and MMP-13). This study showed that 808 nm laser, at both fluences, prevented features related to the articular degenerative process in the knees of rats after ACLT.”

    One Sentence Outcome:In a rat ACL-transection model, PBM helped preserve tissue organization and cartilage-related structure, supporting a biological rationale for ligament-related recovery support.

    Study Parameters:Ligament transection; ; Biphasic dose response

    Device Parameters: wavelength: 808; fluence: 10 50; sessions: 15

    Evidence Level:Level 5 (preclinical animal study)

    Study Type: Rat

    Outcome Direction: Positive / dose-dependent preclinical signal

Author Image - Alon Landa

About the Author
Alon Landa is the CEO and co-founder of MedcoVet, a leader in at-home red light therapy for pets. With over 20 years of experience in medical technology and firsthand involvement in developing the Luma, Alon combines deep technical knowledge with a passion for improving pet health. He regularly collaborates with veterinarians and pet parents to advance photobiomodulation (PBM) care at home.
 📍 Based in Boston, MA
📖Read more from Alon here

Kristy Williams Medical Reviewer Headshot

About the Medical Reviewer
Clinical Focus: Surgery, anesthesia, canine fitness, injury prevention, agility
Kristy Williams brings over 30 years of experience to the veterinary field. Her career began in the 1990s, working as a civilian for the Army Veterinary Corps at RAF Feltwell in England, where she first discovered her passion for animal care and supporting their families. Upon returning to the United States, Kristy pursued her education and graduated in 2005 as a certified veterinary technician after passing the national exam. She has since gained extensive experience in both general practice and emergency/referral practices.
Read More about Kristy here.