Alopecia Studies Library
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The effectiveness of low-level laser therapy for androgenetic alopecia
By Adil A, Godwin M et al.
• 2017
• Journal: Journal of Dermatological Treatment
Abstract: Systematic review and meta-analysis showing LLLT significantly increases hair density in androgenetic alopecia.
One Sentence Outcome:LLLT significantly increased hair density compared to control
Study Parameters:Multiple trials analyzed
Device Parameters: 630–660 nm laser; ~5 mW per diode; power density ~3–5 mW/cm²
Evidence Level:High
Study Type: Systematic Review & Meta-analysis
Outcome Direction: Positive
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Efficacy of low-level laser therapy in the treatment of androgenetic alopecia
By Jimenez JJ et al.
• 2014
• Journal: American Journal of Clinical Dermatology
Abstract: Randomized controlled trial demonstrating increased terminal hair density in men and women treated with LLLT.
One Sentence Outcome:Increased terminal hair density in men and women
Study Parameters:Randomized, sham-controlled
Device Parameters: 650 nm laser helmet; total output ~100–200 mW; ~5 mW per diode; ~4–6 mW/cm²
Evidence Level:High
Study Type: RCT
Outcome Direction: Positive
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HairMax LaserComb laser phototherapy device in the treatment of male androgenetic alopecia
By Leavitt M et al.
• 2009
• Journal: Clinical Drug Investigation
Abstract: Sham-controlled trial showing statistically significant hair growth with a laser comb device.
One Sentence Outcome:Statistically significant increase in hair growth vs placebo
Study Parameters:Sham-controlled
Device Parameters: 655 nm laser comb; 7–9 beams at ~5 mW each; ~3–5 mW/cm²
Evidence Level:High
Study Type: RCT
Outcome Direction: Positive
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Low-level laser therapy for hair loss: mechanisms and efficacy
By Avci P et al.
• 2014
• Journal: Lasers in Surgery and Medicine
Abstract: Review describing mitochondrial stimulation and hair follicle cycling mechanisms underlying PBM.
One Sentence Outcome:Supports mitochondrial stimulation and hair follicle cycling
Study Parameters:Literature review
Device Parameters: 630–680 nm (typical PBM range); variable power 1–100 mW; dose-dependent
Evidence Level:Moderate
Study Type: Review
Outcome Direction: Positive
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Low-level laser therapy for the treatment of female pattern hair loss
By Lanzafame RJ et al.
• 2013
• Journal: Lasers in Surgery and Medicine
Abstract: Randomized trial showing significant increase in hair density in women with androgenetic alopecia.
One Sentence Outcome:Significant increase in hair density in females
Study Parameters:Randomized trial
Device Parameters: 655 nm laser; ~5 mW per diode; multi-diode array; ~4–6 mW/cm²
Evidence Level:High
Study Type: RCT
Outcome Direction: Positive
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Hair regrowth and increased hair tensile strength using the HairMax LaserComb
By Satino JL, Markou M
• 2003
• Journal: Journal of Cosmetic Laser Therapy
Abstract: Controlled study demonstrating improved hair regrowth and strength following laser treatment.
One Sentence Outcome:Improved hair regrowth and tensile strength
Study Parameters:Controlled study
Device Parameters: 650 nm laser comb; ~5 mW per beam; low power density ~3–5 mW/cm²
Evidence Level:Moderate
Study Type: Controlled Trial
Outcome Direction: Positive
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Effect of low-level light therapy on hair growth in patients with androgenetic alopecia
By Kim WS et al.
• 2013
• Journal: Annals of Dermatology
Abstract: Double-blind trial showing increased hair density using an LED helmet device.
One Sentence Outcome:Significant increase in hair density
Study Parameters:Double-blind trial
Device Parameters: 630–660 nm LED array; total output ~100 mW; ~3–6 mW/cm²
Evidence Level:High
Study Type: RCT
Outcome Direction: Positive
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Low-level laser therapy accelerates hair regrowth in a mouse model of alopecia
By Wikramanayake TC et al.
• 2012
• Journal: Lasers in Surgery and Medicine
Abstract: Animal study showing stimulation of hair regrowth via PBM in alopecia model.
One Sentence Outcome:Stimulated hair regrowth in alopecia model
Study Parameters:Mouse model
Device Parameters: 655 nm red light; low power ~5–50 mW; animal exposure model
Evidence Level:Moderate
Study Type: Animal Study
Outcome Direction: Positive
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Effect of laser irradiation on hair growth
By Mester E et al.
• 1967
• Journal: Initial experimental reports
Abstract: Early experimental work first demonstrating laser-induced hair growth effects.
One Sentence Outcome:First observation of laser-induced hair growth
Study Parameters:Early experiments
Device Parameters: ~694 nm early ruby laser; low power experimental exposure
Evidence Level:Early
Study Type: Experimental
Outcome Direction: Positive
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Low-level laser therapy for androgenetic alopecia: a review
By Gupta AK, Foley KA
• 2017
• Journal: Dermatologic Surgery
Abstract: Review summarizing consistent positive outcomes of PBM across alopecia studies.
One Sentence Outcome:Consistent positive outcomes across studies
Study Parameters:Review
Device Parameters: 630–660 nm range; typical PBM outputs 5–100 mW; dose dependent
Evidence Level:Moderate
Study Type: Review
Outcome Direction: Positive


